Top latest Five Understanding Drug Metabolism: Principles and Processes Urban news
This reactive epoxide intermediate may perhaps respond with amino acid residues of a CYP enzyme to kind drug-CYP (drug-protein) adducts (Scheme 6, pathway C). The formation of your drug-CYP adducts may or may not demonstrate a time-dependent inactivation of your catalytic action of this CYP enzyme, dependant upon the covalent binding in the reactiv